【醫生信箱】Q25. Phosphatidylserine (腦磷脂)對 ADHD/ASD 有冇幫助？

Q25. 想請教ADHD/ASD兒童服用磷脂醯絲氨酸 (腦磷脂、PS) 有冇幫助？

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相比起 ASD，PS 對於 ADHD 既 research 會比較多。

https://pmc.ncbi.nlm.nih.gov/articles/PMC9208377/

呢篇係一篇 review article, 將相關既研究 combine 嚟 review

咁有四個重點

- "Children with ADHD have lower levels of phosphatidylserine in serum, as well as the basal ganglia and prefrontal cortex."

- "Results of the meta-analysis showed a statistically significant effect of 200–300 mg/day of phosphatidylserine on symptoms of inattention relative to placebo" (對專注力不足有機會有幫助)

- The effects of phosphatidylserine on overall symptoms of ADHD (ES 0.76; 95% CI: −0.07 to 1.60; p = 0.07) and hyperactivity-impulsivity (ES 0.24; 95% CI: −0.04 to 0.53; p = 0.09) were not statistically significant (整體講又可能無太大幫助, 尤其是過動/衝動既行為問題)

- additional research in this area is warranted (須要進一步研究) ✍🏻撰文：精神科專科醫生 張正平醫生